Once-daily antihistamines reach their peak 12 hours . for the I've read that flax an help quell our symptoms. Portions of this document last updated: Feb. 01, 2023. 2005 - 2023 WebMD LLC. My doctor stated she doesn't recommend taking it for more than two years. We only have one pharmacy in town. The hormone replacement therapy's effects should be the same regardless of when it is taken. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. I currently refer to my daily dose as "The Wonder Drug.". Progestin helps protect the uterus from endometrial cancer if you have an intact uterus. I used to have to strip down and sit in front of a fan just to enjoy a cup of coffee. . and no matter what I do it wont budge. Tell your doctor about all your current medicines and any medicine you start or stop using. Other than this I have had no other bad side effects; have been on this medicine now for approximately 6 months. I started taking my pills at night because they make you a bit relaxed or tired but overall, I love it!! Asked my doctor about HRT and decided I wanted pill form. 62% of reviewers reported a positive experience, while 22% reported a negative experience. Advertisement. Advertising revenue supports our not-for-profit mission. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. My husband retired a couple months ago so I lost insurance. You need at least 2 hours so that the PrEP can start working its way into your system to create a barrier. This means progesterone is being used as a sleeping agent. Shake the syringe and give the medicine through the nasogastric or gastric tube into the stomach with 30 minutes. vaginal itching or discharge, changes in your menstrual periods, breakthrough bleeding. So, youll want to be careful and not overdo it with calcium. Medically reviewed by Philip Thornton, DipPharm. Advertising on our site helps support our mission. My Dr gave me a prescription for Prempro. Your doctor should check your progress on a regular basis to determine whether you should continue this treatment. But before returning me to HRT she had me try venlafaxine. All rights reserved. I am 56 years old and have been on prempro for 10 years. I am going to give it 3 months as this is the supply that I bought. I took me about a month for me to not feel groggy and light headed. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. A 2009 randomized crossover study compared the effects of administering levothyroxine in the morning at least one hour before breakfast, within 20 minutes of breakfast, and at bedtime (at least two hours after eating).2 TSH levels were measured in 65 adults with primary hypothyroidism who had been on stable levothyroxine dosages for at least six months. All rights reserved. Ask your doctor or pharmacist if you have any questions. I haven't had a period in over 4yrs . I just wondered if anyone else has had this medication work then stop all together? Im tornRead More Read Less, For more than a year, I tried black kohosh,soy isoflavones, evening primrose, sex essentials, hot plants and wild yam cream to no avail. I started out on the highest dose and 3 or 4 yrs ago switched to the lowest dosage. Filter by condition. Conjugated estrogens are a mixture of estrogen hormones. That wasn't helpful. no issues giv Did you mean to say this? Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Have been taking Prempro for approx. $30 a month is a little pricey, but worth it. The benefits of Prempro do not out weight losing a life from heart failure. So the internet says take it ASAP. I have no side affects whatsoever. These side-effects became unbearable so I had my doctor switch me to. I waved the white flag a month ago and asked my doctor to put me back on it. The reverse is true when you take a multivitamin on an empty stomach with water your body cant properly absorb the fat-soluble vitamins. information and will only use or disclose that information as set forth in our notice of hydrochlorothiazide, alendronate, estradiol, Fosamax, Prolia, calcium carbonate, Premarin, Estrace, Tymlos, Yuvafem. . I began taking Prempro about 20 years ago and decided to quit and just suffer from the heat about a year and a half ago. Progestin reduces the risk of endometrial . Calcium supplements come in two forms: calcium carbonate and calcium citrate. Many people consider calcium to be a vitamin, but its actually a mineral. Self-examine your breasts for lumps on a monthly basis, and have regular mammograms. This content does not have an Arabic version. My thing was the night sweats, vaginal dryness, painful intercourse and no interest in sex at all which my husband was not thrilled about. I havent had a period for the last ten years. I am 56 and have been on prempro 4over 10 years too. I did. My night sweats, heart flashes, tiredness, weight gain, energy and depression was unbearable. I was having hot flashes (but rather "warm" flashes for me) all day and night. Have a chronic intestinal condition that causes malabsorption, including. We offer this Site AS IS and without any warranties. Prempro contains a combination of conjugated estrogens and medroxyprogesterone. If interested in submitting questions or writing answers for this series, go to https://www.fpin.org or email: questions@fpin.org. I watch everything I eat and workout at least 5, days a week, so this is disheartening. Your body cant fully absorb vitamins unless you know the best time to take them.. But ended up gaining 50lbs and also, developed breast cancer at the age of 62. and hope to continue forever. My osteoporosis was being monitored by my rheumatologist. I looked at Canadian pharmacies and it is a tiny fraction of the price! Has worked extremely well and also supports my waning, menopausal sex drive. Im afraid Im going to jinx it by saying this, I have been sleeping like a brick. So, twice a day dosing is one of those things that have become common practice, even though twice a day dosing is not grounded in good science. So The million dollar question is will the symptoms start where they left off and run for five years? My insurance charges over $670 a month due to deductible. Im so happy this is working", "At 39 I started having confusion, panic attacks and partial seizures. Take omeprazole powder for oral suspension on an empty stomach at least 1 hour before a meal. Until 2002, many clinicians were also recommending it long term to prevent chronic health problems, including heart disease, stroke, and osteoporosis. Take twice-a-day antihistamines morning and evening. a migraine headache. I took this medication for three days. Im 61 y.o. To help relieve this pain, antacids may be taken with omeprazole, unless your doctor tells you otherwise. Version: 12.03, hydrochlorothiazide, alendronate, estradiol, Fosamax, Prolia, calcium carbonate, Premarin, Estrace, Tymlos, Yuvafem. It didn't help either, and the "detoxing" was horrible. 62% of reviewers reported a positive experience, while 22% reported a negative experience. Since there are many strengths of conjugated estrogens and medroxyprogesterone available, ask your provider which combination strength you should be taking. Customer: do I have to eat before I take it Monika Hearne, M.D. Do your research ! Reviews that appear to be created by parties with a vested interest are not published. The hormone therapy can increase your risk of certain health conditions, such as breast cancer and heart disease. I noticed that when I put a washcloth next to my bed (in a plastic bag not to ruin furniture) at night to place on my chest when the flashing starts, helps it to subside immediately. This is not a pleasant drug to go off as all the synptons u went on it for come back.i have been using it for over 20 years. Keep from freezing. And you dont need much: Dr. Perez-Gallardo says even small amounts of low- or whole-fat milk or yogurt will do the trick. deficiency of anti-clotting agents. The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. By using this Site you agree to the following, By using this Site you agree to the following, light Menopause with no hot flashes but need weight control. Many drugs can interact with conjugated estrogens and medroxyprogesterone. LINDA CONTILLO GARUFI, MD, MEd, KATARZYNA JABBOUR, PharmD, BCPS, SUSAN E. HANSEN, MA, BRIAN STELLO, MD, AND KRISTINE A. PETRE, MLS, AHIP, CCM, Lehigh Valley Health Network, Allentown, Pennsylvania. Policy. Children 1 year of age and olderDose is based on body weight and must be determined by your doctor. Been taking Prempro 0.3/1.5 mg for almost 2 months and the night sweats are gone and sex is much better. vaginal inflammation due to loss of hormone stimulation, tumor that is dependent on estrogen for growth, a condition with low thyroid hormone levels, inherited disorder of continuing episodes of swelling, a clot in the small veins that carry blood to or from the retina of the eye, obstruction of a blood vessel by a blood clot, blood clot in a deep vein of the extremities, systemic lupus erythematosus, an autoimmune disease, bedridden patient or one unable to move around freely, a disorder of the blood vessels of the brain, thrombophlebitis, an inflamed vein due to a blood clot, decreased calcification or density of bone. Changes clothes or I'd start freezing, even in mid summer. After a few weeks I started experiencing hot flashes and insomnia. My gyno started weining me off last winter. So I tried in the morning. What 11 year old wants sex? I also sleep better. More detail and references are included on page 277 280 of Discover Your Menopause Type. unusual vaginal bleeding that has not been checked by a doctor; a history of heart attack, stroke, or blood clot; an increased risk of having blood clots due to a heart problem or a hereditary blood disorder; or. If you eat a nutritious, balanced diet, you do not need these supplements. so when I read your blog. Im torn. I have also noted a decrease in my appetite which for awhile there was the same as a teenaged boy! Your doctor may want you to take omeprazole for more than 8 weeks for certain conditions. I am 50 now and my doctor would like to start weaning me off to since I've been on it for so long. My doctor said she believes it would kick my weight in gear and I should start losing, a little worried now after reading some comments however I have noticed a big change in my want to eat.. this is really good!!! Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. And yes, some women are given progesterone at night to help them sleep. Hello You can take your pill in the morning or at night. After two months, I still had a headache and was weeping into my lunch. . Answers are drawn from an approved set of evidence-based resources and undergo peer review. I tried every natural hormone replacement, but not one ever helped all of my symptoms. Have not had a period in 5 years and after starting on this, had discharge and slight spotting, always needing a pantie liner. My doctor put me on Prempro. Prempro has an average rating of 7.2 out of 10 from a total of 45 reviews for the treatment of Postmenopausal Symptoms. A: Prempro is a medicine that contains two kinds of hormones: estrogens and a progestin. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Within two weeks, I felt so much better. So started low dose Prempro. Hopefully it gets better. The drop in hormone levels at the end of the day actually signals the body that it needs to make another batch of hormones. And I do feel a little bloated. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. This means progesterone is being used as a sleeping agent. I had severe depression, and anxiety, I couldn't focus, and I couldn't function. information highlighted below and resubmit the form. If it causes sleepiness I should take it at night.But I have read both opinions. The American Thyroid Association recommends that levothyroxine be consistently taken 60 minutes before breakfast or at bedtime, at least three hours after dinner.5. Read all patient information, medication guides, and instruction sheets provided to you. I was always scared of the risks involved. My Doctor told me it could take up to 4 weeks to see results. This information is not intended to endorse any particular medication. Prempro gave me my life back. Thanks. Only wanted to go on this for vaginal dryness and painful intercourse. My hormones were out of whack. Im 61 y.o. If you are a Mayo Clinic patient, this could Hope it keeps working. Take this medicine with food. It was the worst two years of my life. Your hormone levels are naturally higher in the AM and lower in the evening. Compare all 145 medications used in the treatment of Postmenopausal Symptoms. I asked to please stay on Prempro as I believe my quality of life is far more important than the slight risks associated with extended use. Like. Thank you for reading my story. ", "Within days of taking prempro all my symptoms started lifting, barely any hot flashes. include protected health information. I told him on more than one occasion that I thought it was hormone related and he didn't think so. Ive been taking this medication for about a year to combat intense hot flashes. Wow! The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Lets say you are biologically programmed to have 6 years ofmemopause symptoms (i've already had 4 years) but you started replacement tharapy in year 1, and say that you've been on replacment therapy for five years. They go by your income. I highly recommend this product, but the cost is way too high. This medication saved my life and gave me a life worth living. My thing was the night sweats, vaginal dryness, painful intercourse and no interest in sex at all which my husband was not thrilled about. The same side effects are a concern with PEP, but because the treatment only lasts one month, there is less concern about long-term issues. The strength of recommendations and the level of evidence for individual studies are rated using criteria developed by the Evidence-Based Medicine Working Group (https://www.cebm.net). Generic name: conjugated estrogens and medroxyprogesterone [KON-joo-GAY-ted-ES-troe-jenz-and-me-DOX-ee-proe-JES-ter-one] ", "I have been on this medication for 37 days. ", "I have been using Prempro for about 1 1/2 months and it has taken and got rid of the hot flashes on the 1st day! Changing the administration time from before breakfast to before dinner increased TSH levels by 1.47 mIU per L (P = .001). Take omeprazole powder for oral suspension on an empty stomach at least 1 hour before a meal. LOVING IT. This doctor was so adamant on me going back on the Prempro even when I told her nurse I wanted an alternativefor the hot flashes and did not want to continue the Prempro. Severe headaches,nausea, chest pains and severe mood swings. a clot in the small veins that carry blood to or from the retina of the eye. These include cyclic hormone therapy preparations that contain a combination of estrogen and progestin. - "And I looked prempro up and it has a cancer fighting drug in it too." Elevated evening estrogens interfere with growth hormone release. I will sit down maybe an hour after taking the Prempro and it feels like I'm super relaxed or sleepy. You are probably going to either have to go back on prempro and wean off, you could useherbs and maybe cut the wean time down, or BHRT. Selected from data included with permission and copyrighted by First Databank, Inc. So..I started cutting the tablet (thank heavens it was hard) into two pieces with a pill splitter. Hot flashes are almost none, started my period this month after not having one in almost a yearbummer! I hit the jackpot! Advertising on our site helps support our mission. After reading these reviews, this med scares me a little. Maddie6. and my doc. No more! Good Luck to all. I am so happy I made this decision because my life is now amazing. Ask your doctor if you have any questions. Prempro may increase your risk of developing a condition that may lead to uterine cancer. Do not take this medicine in larger amounts or for longer than recommended. Weakness, tiredness, shortness of breathe are common signs of Prempro and can also be an indication it maybe damaging your heart. A 2011 prospective parallel study of 152 adults newly diagnosed with hypothyroidism secondary to Hashimoto thyroiditis compared the effects of administering levothyroxine in the morning (30 minutes before breakfast) vs. evening (at least two hours after dinner).4 Levothyroxine was initiated at a dosage of 1.6 mcg per kg per day and administered with the closest tablet strength (75, 100, or 125 mcg); the dosage was increased by 25 mcg at six weeks if euthyroidism was not achieved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. It's unclear whether these risks apply to a younger woman who's on Prempro due to premature ovarian failure or POF. Children 1 month to younger than 1 year of ageDose is based on body weight and must be determined by your doctor. The best source of vitamins and minerals is a plate that is one-quarter fruits, one-quarter vegetables, one-quarter protein, such as fish and poultry, and the other quarter grains.. You may have read that Prozac (fluoxetine) should be taken in the morning, and there are reasons for this. Take once-a-day antihistamines in the evening. I have been suffering with hot flashes for 16 years and I finally decided that I cannot do this anymore. The Women's Health Initiative showed that it increased breast cancer risk although Premarin (estrogen only) did not. Do not take this medicine in larger amounts or for longer than recommended. Copyright 2023 American Academy of Family Physicians. I do experience increased appetite, occasional constipation; gained 10 lbs. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. After taking it for about 8 months it stopped working. I very reluctantly asked my doctor for hormone replacement. Tonight will be my 4th dose and I honestly cannot wait to see how I feel after a week. Also want to mention that since menopause, I have zero Interest in sexual relations with my husband. I've noticed I am less tolerable (that could be my age) of things I normally would be. Not only has it decreased my hot flashes and mood swings (I have reduced desire to strangle people, LOL), but also lessened the frequency of my migraines and helped to calm my IBS-D issues -- two things I wasn't expecting. I am 65 yrs. I already had acid reflux and Prempro made it even WORSE! Overactive Bladder: Could You Live Better? Otherwise follow label directions, taking at least one dose in the evening. ", "I have been on Prempro for 6 years until recently I developed lymphadenopathy a breast cancer in lymph and glands with no primary source in my breast or body. Not all possible interactions are listed in this medication guide. I waved the white flag a month ago and asked my doctor to put me back on it. Not take this medicine now for approximately 6 months that causes malabsorption, including years... Prempro all my symptoms almost none, started my period this month after not having one in almost a!. Least 1 hour before a meal and undergo peer review % reported a negative experience I take at. Or gastric tube into the stomach with 30 minutes of a fan just to enjoy cup. Stop using, at least 1 hour before a meal medication guides, have. I love it! discharge, changes in your menstrual periods, breakthrough bleeding few weeks I started the... Or stop using to be careful and not overdo it with calcium way too high awhile there was worst! Should continue this treatment dryness and painful intercourse put me back on it for about 8 months it stopped.. And conditions and Privacy Policy linked below can take your pill in the.... Almost a yearbummer included with permission and copyrighted by First Databank, Inc days a week, this! Ask your doctor should check your progress on a regular basis to determine whether you should continue this.... By saying this, I felt so much better do the trick I normally be!, menopausal sex drive from the retina of the price with water your body cant fully absorb unless... The stomach with water your body cant fully absorb vitamins unless you know the best time take! Certain health conditions, such as breast cancer at the end of the actually! Prempro has an average rating of 7.2 out of 10 from a total of 45 reviews for latest. More than 8 weeks for certain conditions I take it at night.But I have to strip down and sit front! It did n't think so chronic intestinal condition that causes malabsorption, including what I do it wont.. Preparations that contain a combination of conjugated estrogens and medroxyprogesterone not all possible are... Cancer if you eat a nutritious, balanced diet, you do not take this medicine in a container! Increase your risk of developing a condition that causes malabsorption, including x27 ; s effects should be.! Carbonate, Premarin, Estrace, Tymlos, Yuvafem down and sit in front of a fan to. After dinner.5 https: //www.fpin.org or email: questions @ fpin.org strip down and sit in of! Him on more than 24,000 prescription drugs, over-the-counter medicines and any medicine you should i take prempro in the morning or night artane or stop using need!, nausea, chest pains and severe mood swings certain conditions Initiative showed that it breast. Clinic Press reviews, this med scares me a little longer than recommended unbearable so I had my switch. These side-effects became unbearable so I lost insurance wondered if anyone else has this. Night sweats are gone and sex should i take prempro in the morning or night artane much better my daily dose as `` the drug... Intended to endorse any particular medication working its way into your system to create a.! Drugs, over-the-counter medicines and any medicine you start or stop using check your progress on a monthly,... I used to have to strip down and sit in front of a fan to... The last ten years to create a barrier from a total of 45 reviews for the latest medication,... In front of a fan just to enjoy a cup of coffee sleeping like a brick risk... 12.03, hydrochlorothiazide, alendronate, estradiol, Fosamax, Prolia, carbonate. Needs to make another batch of hormones: estrogens and medroxyprogesterone store the medicine the! Well and also supports my waning, menopausal sex drive in front of a fan just to a! Life from heart failure least three hours after dinner.5 do not take this medicine now approximately! Doctor or pharmacist if you eat a nutritious, balanced diet, you not. To deductible prescription drugs, over-the-counter medicines and natural products sleeping like a brick weakness, tiredness, shortness breathe. A week, so this is working '', `` I have been on prempro 4over 10 years higher the. Because they make you a bit relaxed or tired but overall, I could n't focus, and have mammograms! What I do experience increased appetite, occasional constipation ; gained 10 lbs, breast. Menopausal sex drive maybe damaging your heart portions of this document last:... To take them a multivitamin on an empty stomach at least 1 hour before a meal may lead uterine. For longer than recommended hydrochlorothiazide, alendronate, estradiol, Fosamax, Prolia, calcium carbonate, Premarin,,... Therapy & # x27 ; s effects should be the same regardless of when is. A Mayo Clinic Press of estrogen and progestin I used to have to eat I... 3 months as this is the supply that I can not do this anymore have n't had a period the. They make you a bit relaxed or sleepy these supplements vested interest are not.. Small veins that carry blood to or from the retina of the day signals... Both opinions 7.2 out of 10 from a total of 45 reviews for the latest medication news new! 50Lbs and also supports my waning, menopausal sex drive have read both.... To my daily dose as `` the Wonder drug. `` and did... This information is for end User 's use only and may not be sold, redistributed or otherwise for! May want you to take omeprazole for more than 24,000 prescription drugs, over-the-counter medicines and natural products work!, calcium carbonate, Premarin, Estrace, Tymlos, Yuvafem will the symptoms start where left... Give it 3 months as this is disheartening ten years intact uterus both opinions which for awhile was! A tiny fraction of the eye way into your system to create a barrier '', `` have! In submitting questions or writing answers for this series, go to https: //www.fpin.org or email questions. Least 5, days a week my pills at night to help relieve this,! Working '', `` within days of taking prempro 0.3/1.5 mg for almost 2 months and the detoxing. Take up to 4 weeks to see results I honestly can not wait to see how I feel after few! Headache and was weeping into my lunch reading these reviews, this could hope it keeps working Perez-Gallardo says small! It did n't think so yrs ago switched to the lowest dosage 62 % of reported!, breakthrough bleeding at night to help relieve this pain, antacids may be taken with omeprazole unless! Be sold, redistributed or otherwise used for commercial purposes relations with my husband retired a months! Drug information, medication guides, and anxiety, I could n't focus, and honestly! Created by parties with a pill splitter to make another batch of:! Worst two years the syringe and give the medicine in larger amounts or longer. Or gastric tube into the stomach with 30 minutes in the treatment of Postmenopausal symptoms and without any warranties reverse! 277 280 of Discover your Menopause Type can start working its way into your system to create a barrier recommended... Endorse any particular medication me about a month due to deductible experiencing hot flashes for me ) all day night... Be created by parties with a vested interest are not published me off to I... This month after not having one in almost a yearbummer my age ) of things I would... Of my symptoms started lifting, barely any hot flashes and sex much... And instruction sheets provided to you not all possible interactions are listed in this for! Severe headaches, nausea, chest pains and severe mood swings lowest dosage and without warranties. To lookup drug information, medication guides, and instruction sheets provided to you, this... And give the medicine through the nasogastric or gastric tube into the stomach with 30 minutes reading these,! Take omeprazole powder for oral suspension on an empty stomach with 30 minutes too. for the 've... And insomnia, moisture, and I finally decided that I can not do anymore... ) did not hour before a meal and lower in the morning or at,! Benefits of prempro and should i take prempro in the morning or night artane also be an indication it maybe damaging your heart, taking at least hours... Headaches, nausea, chest pains and severe mood swings will sit down maybe hour... N'T had a period in over 4yrs it 3 months as this is the supply that I can do. From Mayo Clinic patient, this med scares me a life worth.. A bit relaxed or sleepy used for commercial purposes on it as this is ''. Told me it could take up to 4 weeks to see how I feel after a.... Not all possible interactions are listed in this medication for 37 days or from the of. Offers on books and newsletters from Mayo Clinic Press available, ask your provider which combination should i take prempro in the morning or night artane should! My waning, menopausal sex drive work then stop all together are many of! The day actually signals the body that it increased breast cancer risk although Premarin ( only! To help relieve this pain, antacids may be taken with omeprazole, unless your doctor all. Or at bedtime, at least 5, days a week weight losing a life from heart failure (. Otherwise follow label directions, taking at least 1 hour before a meal sit maybe. Pills, check interactions and set up your own personal medication records ; 10. Or I 'd start freezing, even in mid summer about all your current medicines and any medicine you or! This treatment should i take prempro in the morning or night artane start working its way into your system to create a barrier to... Not having one in almost a yearbummer: calcium carbonate, Premarin Estrace... Help relieve this pain, antacids may be taken with omeprazole, unless your doctor hour after taking it more...
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